Research Projects
Each year, the ExposUM Institute funds research projects focused on the exposome. For each cycle, a priority theme is selected collectively by the Institute’s three councils: the Executive Committee (CoDir), the Research Guidance and Evaluation Council (COER), and the Scientific and Strategic Guidance Council (COSS).
Calls for proposals provide funding for two categories of research projects:
- Standard Research Projects
This category corresponds to the standard project format that provides funding for personnel and operating expenses necessary to produce original results that can be commercialized or published.
Maximum funding amount and duration:250 k€ over 2 years. - Exploratory Research Projects
These projects are designed to launch exploratory and original research initiatives, test hypotheses and approaches that are not typically supported by standard calls for proposals, and produce preliminary results with a view to applying for more ambitious grants at a later stage.
Funding limits and duration:50 k€ over 2 years.
As part of the selection process, each research project is evaluated by international experts. Here is the list of experts who participated in these evaluations.
Research projects are led by the research division of the ExposUM Institute.
Winning Projects
2026 campaign
As it does every year, the AAPR focuses on a priority theme chosen collectively by the Institute’s three councils. For 2026, this theme was: “ Exposome and Behavior.”
Standard Projects
EXPOSURE
Title: The Brownfields of Port-La-Nouvelle’s “Poison Factories”—A Study of Exposure Based on Local Residents’ Practices in Lagoon Environments
Acronym:EXPOISON
Project Leader:Christelle Gramaglia
UMR:GEAU
MONUMENTAL
Title: ExposoMic Approach to Enhance Nutritional Medicine in Mental Health
Acronym:MONUMENTAL
Project Leader:Tasnime AKBARALY
UMR:IDESP
DEP-LOOP
Title: Diet and Depression/Anxiety: Exploring Bidirectional Food Exposome-Behavior Interactions
Acronym:DEP-LOOP
Project Leader:Sylvaine ARTERO
UMR:IGF
EXPOSTA
Title: Social and Environmental Exposome, Immune Response to Stress, and Behavioral Trajectories Associated with Suicidal Behavior
Acronym:EXPOSTA
Project Leader: LENGVENYTEAiste
UMR:IGF
LIFE-MUSC
Title: Lifestyle Influences on the Circulating Exposome and Muscle Deconditioning
Acronym:LIFE-MUSC
Project Leader:Mélissa GENTREAU
UMR:PhyMedExp
ProMINDS-Viet
Title: Promoting Maternal and Infant Nutrition through Digital Solutions in Vietnam
Acronym:ProMINDS-Viet
Project Leader:Agustin MIRANDA
UMR:MOISA
EBD
Title: Oral Exposome, Oral Hygiene Behaviors, and Health Inequalities in Disadvantaged Neighborhoods
Acronym:EBD
Project Leader:Isabelle BOURDON
UMR:MRM
Exploratory Projects
IMMUNE-BEHAV
Title: Proactive Behavioral and Immune Responses to Disease Cues in the Social Exposome
Project acronym: IMMUNE-BEHAV
Project Leader: Arnaud TOGNETTI
UMR: CEEM
UnShockWork
Title: The Impact of Uncertainty Shocks on Cognitive Performance and Work Persistence (UnShockWork): Evidence from Controlled Laboratory Experiments
Project acronym: UnShockWork
Project Leader: Marc WILLINGER
UMR: CEEM
AnthroPox
Title: Alternative Transmission Routes of the Mpox Virus: An Anthropological and Ethnoecological Investigation of Exposure Pathways and Contact Zones Between Humans and Squirrels in the Republic of the Congo.
Project acronym: AnthroPox
Project Leader: Romain DUDA
UMR: CEFE
CARMIN
Title: Eating Habits and Exposure to Metabolic and Inflammatory Risks in Obesity
: Eating Habits and Exposure to Metabolic and Inflammatory Risks in Obesity
Project acronym: CARMIN
Project Leader: Anne-Dominique LAJOIX
UMR: BC2M
IRON-MEN
Title: Characterizing Iron Oxide Nanoparticles in Meningiomas in Relation to Atmospheric Exposure
Project acronym: IRON-MEN
Project Leader: Pierre CAMPS
UMR: GM
BEHAVE-WILD
Title: Behavioral and Environmental Human Activities That Contribute to Antimicrobial Resistance Through Exposure to Wildlife
Project acronym: BEHAVE-WILD
Project Leader: Chloé DUPONT
UMR: MIVEGEC
ADAPT
Title: Accelerating the Elimination of Onchocerciasis in Cameroon: A Systemic and Integrated Approach
Project acronym: ADAPT
Project Leader: Anne Geiger
UMR: INTERTRYP
DIGI-EYE-OMICS
Title: Integrated Multi-omics Analysis of Ocular Surface Stress Caused by Tablet Screen Exposure
Project acronym: DIGI-EYE-OMICS
Project Leader: Frederic Michon
UMR: INM
2025 campaign
As it does every year, the AAPR focuses on a priority theme chosen collectively by the Institute’s three councils. For 2025, this theme was: “ Anticipating exposomic health risks.”
Standard Projects
FAMEXP
Title: Impact of the External and Internal Exposome on Pregnancy and Maternal-Fetal Complications in Women with Rheumatoid Arthritis (RA) and Systemic Lupus Erythematosus (SLE)
Acronym:FAMEXP
Project Leader: Yves-MariePERS
UMR:FHU REGENHAB 2 IRMB
POLLU-DEFECT
Title: Is Exposure to Pollutants During Pregnancy a Risk Factor for Congenital Defects?
Acronym: POLLU-DEFECT
Project Leader: Benoît TESSIER
UMR: IDESP
UnMUtE
Title: Unraveling and Modeling the Worsening of ASD Symptoms Following In Utero Exposure to Environmental Pollutant Residues
Acronym: UnMUtE
Project Leader: Karine LOULIER
UMR: INM
Wa3ve
Title: Workflow for Antibody-Based Analysis and Prediction of Virulence and Emergence
Acronym: Wa3ve
Project Leader: Antoine GROSS
UMR : IRIM
IMPACT-Gen
Title: The Impact of Reservoir Depletion on Plasmodium falciparum Genetic Diversity
Acronym: IMPACT-Gen
Project Leader: Antoine CLAESSENS
UMR: LPHI
EXALTOX
Title: Exposure to Emerging Algal Toxins, with a Focus on Ciguatoxins in Vulnerable Marine Ecosystems Around the World: Threats to Human Health, Diversity and Ecology of Benthic Toxic Species, and Risk Assessment.
Acronym: EXALTOX
Project Leader: Alain LACAMPAGNE
UMR: PHYMEDEXP
RAMAC-One
Title: Antimicrobial Resistance and Street Drugs in Central Africa: A One-Health Approach
Acronym: RAMAC-One
Project Leader: Jérémy CAMPILLO
UMR: TRANSVIHMI
Exploratory Projects
PExAR
Title: Exposure to Air Pollution and the Risk of Preeclampsia During Pregnancy: Current Status in France Over 6 Years (2018–2023)
Project acronym: PExAR
Project Leader: Sylvie BOUVIER
UMR: IDESP
COLOPIFAS
Title: Exposure to PFAS and Colorectal Cancer Metastasis
Acronym: COLOPIFAS
Project Leader: Audrey CASTET-NICOLAS
UMR: IRCM
Evaluation of the Effects of Environmental Pollutants (EPs) and Air Samples on the Pregnane X Receptor (PXR)-Mediated Mitogenic Activity of Colorectal and Hepatic Cancer Cells
Title: Evaluation of the Effects of Environmental Pollutants (EPs) and Air Samples on the Pregnane X Receptor (PXR)-Mediated Mitogenic Activity of Colorectal and Hepatic Cancer Cells
Project Leader: Philippe POURQUIER
UMR: IRCM
An Exposome-Driven Approach to Sustainable Aquaculture: Addressing Environmental Pollution and Health Risks in West Africa.
Title: An Exposome-Driven Approach to Sustainable Aquaculture: Addressing Environmental Pollution and Health Risks in West Africa.
Project Leader: Jean-Christophe AVARRE
UMR: ISEM
Urban-EXAM
Title: Exposure to Arboviruses in Urban Areas
Acronym: Urban-EXAM
Project Leader: Rodolphe HAMEL
UMR: MIVEGEC
CryptENVI
Title: Genetic Diversity, Resistance, Virulence, and Inflammation of Cryptococcus Strains Isolated from the Environment
Project acronym: CryptENVI
Project Leaders: Sébastien BERTOUT, Virginie BELLET, Pascal DRAKULOVSKI
UMR: TRANSVIHMI
2024 campaign
As it does every year, the AAPR focuses on a priority theme chosen collectively by the Institute’s three councils. For 2024, this theme was: “Exposome & Major Societal Challenges.”
Standard Projects
ACTS
Title: Animal Contribution to Schistosomiasis Transmission
Acronym: ACTS
Project Leader: Richard GALINIER
UMR: IHPE
AEISTSA
Title: Environmental Quality, Social Inequality, and Autism Spectrum Disorder: Toward a Better Understanding of Socio-Environmental Inequalities During the Perinatal Period in Autism Spectrum Disorder
Acronym: AEISTSA
Project Leader: Amaria BAGHDADLI
UMR: FHU Neur-Expo
ARrbOCC
Title: Exploration of Innovative Approaches for ARBovirus Detection in the Occitanie Region.
Acronym: ARrbOCC
Project Leader: Yannick SIMONIN
UMR: PCCEI
EAD
Title: Environmental Anomaly Detection and Health Impacts: Addressing PFAS Risks
Acronym: EAD
Project Leader: Pascal NEVEU
UMR: MISTEA
ExpLoRA
Title: The Exposome and Gut Flora as Risk Factors for Rheumatoid Arthritis
Acronym: ExpLoRA
Project Leader: Claire DAIEN
UMR: PhyMedExp
MBUSTANI
Title: The Last Sip of the Mosquitoes in a Garden: Designing and Testing a Low-Tech Device
Acronym: MBUSTANI
Project Leader: Christophe BOETE
UMR: ISEM
PEACH
Title: Pathogen Exposure from Aquifers: An Interdisciplinary Health Case Study in Cambodia
Acronym:PEACH
Project Leader: Sylvain MASSUEL
UMR: G-Eau
PeRSee
Title: Pesticides, Replication Stress, and Cancer
Acronym: PeRSee
Project Leader: Jérôme POLI
UMR: IGH
ROTEXPO
Title: Rotavirus, Environmental Heterogeneity, and Zoonotic Exposure: Implications for Human Health
Acronym: ROTEXPO
Project Leader: Stéphanie JACQUET
UMR: MIVEGEC
THREATS
Title: Health and Food Security Risks Associated with Marine Aquaculture Practices and Their Influence on the Circulation of Antibiotic-Resistant Microorganisms and Pathogens in Floating Farm Socio-Ecosystems
Acronym: THREATS
Project Leader: Gwen PULLIAT
UMR: ARTDev
Exploratory Projects
AquaBiocontrol
Title: Aquaculture-Based Approaches for Schistosome Biocontrol in Madagascar
Acronym: AquaBiocontrol
Project Leader: Paula SENFF
UMR: ISEM
AquaAMR
Project Title: Assessing Exposome Factors in Aquatic Environments for the Spread of Antimicrobial Resistance (AMR)
Acronym: AquaAMR
Project Leader: Julia MOUGIN
UMR: IHPE
BLOODPOL
Title: Blood Characterization of Environmental Pollutants After Exercise in Different Air Quality Conditions: A Field Study
Acronym: BLOODPOL
Project Leader: François FAVIER
UMR: Euromov
ExpoViro
Title: Metagenomics: A Closer Look at Early-Life Exposure to Viruses
Acronym: ExpoViro
Project Leader: Ilka ENGLEMANN
UMR: PCCEI
NoiseHear
Title: Prolonged Exposure to Noise or Co-Exposure to Noise and Pollutants During Pregnancy and Hearing Disorders in Offspring
Acronym: NoiseHear
Project Leader: Jin WANG
UMR: INM
2023 campaign
As it does every year, the call for research proposals (AAP-R) focuses on a priority theme chosen collectively by the Institute’s three councils: the Executive Committee (CoDir), the Research Guidance and Evaluation Council (COER), and the Scientific and Strategic Guidance Council (COSS). For this first year, the theme was: “Emerging Exposome”.
Standard Projects
ZAMBA
Title: Rapid Landscape Changes and Their Impact on Vectors and Zoonotic Pathogens in Wildlife, Humans, and Domestic Animals in the Megadiverse Pantanal and Cerrado Biomes of Brazil
Acronym: ZAMBA
Project Leader: Julio BENAVIDES
UMR: MIVEGEC
ROBOPUSA
Title: Rodent-Borne Diseases and Pesticide Use in Southeast Asia
Acronym: ROBOPUSA
Project Leader: Julien CLAUDE
UMR: ISE-M
RoCoCity
Title: Rodent Control in the City: Health Ecology and (Re)exposure to Rodent-Borne Infectious Agents and Vectors
Acronym: RoCoCity
Project Leader: Gauthier DOBIGNY
UMR: CBGP
PMTfocus
Title: Focus on Persistent, Mobile, and Toxic Chemicals as Substances of Very High Concern: An Emerging Exposome from Resource and Drinking Waters to Humans
Acronym: PMTfocus
Project Leader: Elena GOMEZ
UMR: HSM
EXPOSAHR
Title: Toward a Better Understanding of the Emerging Chemical Exposome: Illuminating the Interplay Between Different Classes of Xenobiotics and the Aryl Hydrocarbon Receptor-Dependent Signaling Pathway
Acronym: EXPOSAHR
Project Leader: Jakub GRUSZCZYK
UMR: CBS
WATERISK
Title: Enrichment of emerging antibiotic resistance—a public health
—in the aquatic environment: toward a genomic,
phenotypic, and evolutionary-based proxy for exposure risk in
a given area
Acronym: WATERISK
Project Leader: Estelle JUMAS-BILAK
UMR: HSM
EXPOMITE
Title: Human Exposure to Bird-Associated Blood-Feeding Mites: Ultimate and Proximal Causes of an Emerging Contrast Between Urban and Farm Environments
Acronym: EXPOMITE
Project Leader: Lise ROY
UMR: CEFE